I'm running a 125 Gallon and I do the same thing. I do about a 35-40% water change every other week (work constraints, otherwise I would do it weekly). I fill it back up straight from the hose, treat it immediately after with some NovaQua and StressZyme, and my Oscars nor water quality has ever had any trouble.
I'm running 2 heaters, though, so that probably gets the temperature back up.
I'm also filtering through about 1,240 Gallons an hour with my filters.
I'm running an AquaClear 110 (500 GPh), an Emperor 400 (400 GPh), and two AquaTech Powerheads (170 GPh) each.
Water quality has never been an issue for me in any of my freshwater tanks. As long as you have good filtration, you're treating your water when you do changes, and you're changing it at minimum once a month, you should be fine.