Jamie, in my FX5 I have Bio Max in 2 trays, and keep in mind that is 4 boxes of Bio Max, and the rest I have full of the cheap scrubbies.
Now the reason I did this was because the scrubbies not only will host the good bacteria, but they are thick enough to filter out the rest of the crap and they don't easily clog. Another benefit to the scrubbies, is you can take them out, squeeze them out, and put them back. They will last years.
So at the end of the day, the media in my FX5 doesn't need replacing for a very long time!