About a week and a half ago Oliver (had since Feb, about 8 in) was acting weird (staying in one corner, not eating- usually BEGGING for food all day!) I right away realized it was the start of HITH (small spot around left nostril) and began aggressive water changes, canister cleaning, and treatment with AFI general cure (he had the same thing shortly after I brought him home in March and cured it within a week, thanks to the advice from here). I realized it was my fault due to a long weekend where his water change was delayed about 2 days longer than the usual 75% weekly. That will teach me. So, water changes, meds, he was getting back to normal after a few days. But now the past 2-3 days he's been even worse than before, the spot on his nose hasn't really gotten any bigger, it had actually started improving, and I've continued with water changes every other day. I'm not sure what else do at this point, he hasn't eaten or really moved from one area of the tank in 2 days. Water chemistry is all great nitrite 0ppm, nitrate 0 ppm, ammonia 0ppm. I'm going to try to attach pictures now. 65 gallon tank (i know small for a full grown, was told it was 80 when i bought it) fluval 305 and hob filter.